Pathology EMQ template.

Name: Vishal Navani

Candidate number: 522925

Theme: Myeloproliferative Disorders

OPTION LIST

A	Myeloma	I	Antiphospholipid syndrome
B	Chronic Lymphocytic Lukaemia	J	Chronic Myeloid Lukaemia
C	Secondary Polycythaemia	K	Myeloma
D	Amyloidosis	L	Myeloproliferative Disorder
E	Aplastic anaemia	M	Burkitt’s Lymphoma
F	Polycythaemia Vera	N	Essential Thrombocythaemia
G	Non-Hodgkin’s lymphoma	O	Amyloidosis
H	Hodgkin’s lymphoma	P	Myelofibrosis

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 60 year old man presents with itching, headaches and nosebleeds. On examination you find a plethoric face, engorged fundal vessels and splenomegaly. What’s the diagnosis?

2. A 25 year old man presents with weight loss and night sweats and massive splenomegaly. You find a new BCR-ABL fusion gene on molecular studies. What’s the diagnosis?

3. A group of disorders that arise from a profileration of a haematopoietic stem cell line in the bone marrow

4. A patient presents with recurrent deep vein thrombosis and transient ischaemic attacks. You prescribe aspirin and hydroxycarbamide. What are you trying to treat?

5. A patient presents with characteristic hypermetabolic symptoms (fever, night sweats, weight loss). They also have anaemia and are prone to recurrent infections. You find teardrop and leucoerythroblasic cells on the film, and a trephine bone marrow biopsy confirms your diagnosis. What has the patient got?

ANSWERS

1. F

2. J

3. L

4. N

5. P